Stem cell research
Stem cell researcher to develop cellular therapy for digestive disorders
MARCH 22, 2016
Tracy Grikscheit awarded $7.1 million grant by the California Institute of Regenerative Medicine
Tracy Grikscheit hopes to reduce or remove the requirement for immunosuppressive drugs.
Tracy Grikscheit principal investigator with USC Stem Cell and The Saban Research Institute of Children’s Hospital Los Angeles, has received a $7.1 million grant from the California Institute of Regenerative Medicine Translational Research program to develop a cellular therapy for the treatment of nerve disorders of the digestive system.
These disorders, called enteric neuropathies, include degenerative neuromuscular conditions as well as those caused by a deficient or missing nerve supply to the intestines. Currently, in many cases the only treatment is removing segments of intestine that do not have a properly formed nervous system.
“Our goal is to develop an ‘off the shelf’ cellular therapy to treat enteric neuropathies before patients require surgery or to rescue patients who still have symptoms following surgery,” said Grikscheit, who is also an associate professor of surgery at the Keck School of Medicine of USC and the USC Viterbi School of Engineering.
Working with human induced pluripotent stem (iPS) cells that have the ability to develop into many human cell types, Grikscheit proposes to generate nerve cells from “superdonor” iPS cell lines that are immunologically matched to a large portion of the population. Because these cells would match many patients, Grikscheit hopes to reduce or remove the requirement for immunosuppressive drugs that are often required for transplantation.
This cellular treatment, called Advanced Superdonor Cellular Enteric Neuropathy Therapy, could replace absent or diseased components of the enteric nervous system — the cause of medical conditions such as Hirschsprung disease. The work will include collaboration with scientists at Cedars Sinai Medical Center, University of Michigan and Cincinnati Children’s Hospital. Grant reviews made available publicly online praised the team as having “great expertise,” noting that “the team could perhaps be the best in the world for this indication.”
“The goal of our translation program is to support the most promising stem cell-based projects and to help them accelerate that research out of the lab and into the real world, such as a clinical trial where they can be tested in people,” said Jonathan Thomas, chair of the CIRM board. “The projects that our board approved today are a great example of work that takes innovative approaches to developing new therapies for a wide variety of diseases.”
Regrow oesophagus to join gap
Saturday, Apr 9th 2016
Young man becomes the first patient in the world to regrow his oesophagus after surgeons rebuilt his throat following car crash
1/ The un-named man suffered devastating injuries in a following a car crash which destroyed his oesophagus. 2/ Surgeons at the time fitted metal plates to the man’s throat but these corroded, again threatening his life. 3/ Medics replaced these plates with cheap metal stents and covered them over some donated human skin. Amazingly, the skin samples grew with the aid of the patient’s own platelets, regenerating his shattered oesophagus.
A young man has become the first patient in the world to regrow an oesophagus inside his body. Doctors last night welcomed the breakthrough as a milestone in regenerative medicine, which offers particular hope for those suffering from oesophageal cancer. Experts, including a British-trained doctor, built a simple scaffold from cheap metal stents and human skin – and, to their surprise, the man’s body healed itself.
The un-named victim suffered devastating injuries in a car crash ago and when the original repair failed, a British-trained doctor had to use a pioneering new technique to refashion the man’s oesophagus allowing the skin cells to regenerate, allowing him to swallow normally. The patient, who has not been named, was 24 when he was taken to hospital with a severely damaged oesophagus – the food pipe which connects the mouth to the stomach. Five years earlier, metal plates had been inserted into his spine after a car accident. These had been corroded, leading to a huge abscess in his chest which attacked his oesophagus. Surgeons tried several times to patch up the tube, but it had become completely disconnected, leaving a 2in gap which was impossible to reconnect.
Doctors were amazed that after four years, when they removed the metal stents, the oesophagus was completely repaired, file photo
Professor Kulwinder Dua, the gastroenterologist who carried out the operation, said the result promises to change the way scientists view regenerative medicine. Until now, experts have focused on harvesting stem cells – ‘blank’ cells which can act as a repair kit for the body – and altering them before putting them back into a patient. But Professor Dua, who trained at Aberdeen University before moving to the US, said the body seems to have its own ability to regenerate organs as long as there is a structure for them to build around.
He added: ‘If you cut your finger you do not spray it with stem cells, it heals itself. The blood is flowing with stem cells and it has the ability to do remarkable things … You put the ingredients together, you put it in the oven and it comes out fine.’ Professor Dua, whose results appear in the Lancet medical journal today, said the technique could be used to treat oesophageal cancer, which affects around 9,000 Britons a year. If trials are successful it could become widely used.
Professor Paolo De Coppi, head of surgery at London’s Great Ormond Street Hospital, said: ‘While this is only one patient it is very promising indeed. This technique is cheaper, simpler and most importantly safer for the patient than engineering tissue using stem cells.’
Girl, two, known as ‘Bubbles’ who suffers 14 serious medical conditions including a tethered spinal cord and a missing right ear has to see 70 different doctors
A two-year-old girl who has already had to endure gruelling spinal cord surgery faces a lifetime of operations due to the staggering 14 serious medical conditions she is currently battling.
Anabela Kleyn may seem like your average toddler with her cheeky smile but she has been described by doctors as ‘medically complex’ given the rare number of conditions she was diagnosed with shortly after birth.
She currently sees up to 70 specialists at Sydney Children’s Hospital due to a long list of conditions including limb defects, additional ribs, being born without her right ear, spina bifida and issues with her throat that can often stop her eating and breathing.
Two-year-old Anabela Kleyn has been diagnosed with 14 medical conditions including limb defects, additional ribs, being born without an ear, spina bifida and issues with her throat that stop her breathing. None of these serious issues were picked up when her 34-year-old mother Sarah Pearce was pregnant and only came to light when Anabela had to have surgery to connect her stomach to her food pipe just 48 hours after she was born. She underwent gruelling spinal cord surgery at the end of last year to de-tether her spinal cord and remove a lipoma tumor.Anabela – whose nickname is Bubbles – will already have to have another 10 major surgeries by the time she is 12. She was also diagnosed with permanent sleep apnoea in February, which means she has to sleep with a machine mask so she doesn’t stop breathing every two minutes. ‘Since she was born she has been diagnosed with 14 separate medical conditions, including a very rare condition called VACTERL – it’s been really stressful,’ Ms Pearce told Daily Mail Australia.’It’s quite unique having all of these conditions in the one little body. She sees up to 70 specialists and presents to about 14 different clinics within the Sydney Children’s Hospital.’
None of her issues were picked up when her mother Sarah Pearce was pregnant and only came to light when Anabela had to have surgery to connect her stomach to her food pipe just 48 hours after she was born.Ms Pearce, who is a single mother, is unable to work because Anabela needs full time care. ‘She needs to be watched constantly,’ she said. ‘Eating is an issue because she chokes and when she’s moving a lot and breathes in her trachea collapses and she starts to gasp.’ The stress of keeping on top of Anabela’s long list of conditions and hospital appointments has been an emotional struggle for her mother ‘It’s so hard because I can’t fix her, I can’t fix my baby,’ an emotional Ms Peace said. ‘It’s just a roller-coaster. I never thought I’d be in a situation like this. It’s left me feeling scared and frightened.
‘Mentally she is bright as a spark. She is amazing, she is so brave and strong – that’s what makes it easier.’
Anabela was also diagnosed with permanent sleep apnoea in February, which means she has to sleep with a machine mask so she doesn’t stop breathing every two minutes. Ms Pearce had to leave her family and friends to move from the Blue Mountains to Sydney just so they could be close to the children’s hospital. Being a single parent with no steady income, Ms Pearce manages to survive on $1,200 a fortnight in government benefits ‘Anabela has everything she needs, I go without so I make sure I can provide for her,’ she said A friend of Ms Pearce’s set up a crowd-funding page last month to help cover the expensive and rising cost of Anabela’s critical medical equipment, including a $2,000 CPAP machine to help her breath at night.
Sydney-based Conti Property Group. ( http://contipropertygroup.com.au/). found the GoFundMe page and donated enough money to buy most of the medical equipment – something Ms Pearce says she will be forever grateful for. Ms Pearce says she has also relied heavily on the support of a birth defect website created by Steve Wyles to deal with the emotional struggles.
For more information or to donate money to Anabela Kleyn,
From left, parents Evan and Suzanne Dapo with their 8-week-old daughter Annalise Dapo and WakeMed pediatric surgeon Dr. J. David Hoover all laugh at the question if the Dapo’s daughter had become a “magnet” for attention during a Thursday interview in the pediatric ward at WakeMed Hospital, Raleigh. The laughter was generated because of a medical breakthrough by Dr. Hoover and staff at WakeMed Pediatrics in the repair of Annalise’s incompletely formed esophagus between her mouth and stomach by stretching the two ends to meet by use of attracting magnets slowly drawing together, thereby avoiding more serious surgery.
RALEIGH-They took turns cradling baby Annalise before a firing line of video-cams and photographers recording the scene in an intensive care unit at WakeMed Hospital in Raleigh. As Annalise enthusiastically sucked her formula bottle, mom, dad and doctor fielded questions about the lifesaving procedure performed for the first time in the United States.
The 8-week-old was born at WakeMed with a partially missing esophagus, or foodpipe, which came to a dead end. Lacking about 1.5 inches of esophagus, the newborn survived by means of feedings through a gastric tube inserted through a port in her side. Less than two weeks ago, WakeMed’s Dr. J. David Hoover, a pediatric surgeon, fused the baby’s two disconnected foodpipe sections, making the repair without surgery.
Hoover pulled it off by inserting magnets into the two blind sections of esophagus and allowing magnetic force to pull both ends together to create a single organ. On Friday, he demonstrated the magnet device, letting the magnetic nubbins vibrate as they drew near and then snapped together. The magnets used on Annalise were removed Monday, and she took her first sip later that day. By Friday, Annalise imbibed formula like a pro.
“It’s definitely a medical breakthrough,” Hoover said Friday. “And their hospitalization bill is on the magnitude of hundreds of thousands of dollars less.” Annalise will be going home to Wake Forest on Sunday, at a tender age of 60 days. Had surgery been required, she would have been sedated for weeks and hospitalized several more months. The pint-sized pioneer is the first to undergo nonsurgical fusion of the esophagus in the United States.
“It was jaw-dropping,” said Annalise’s father, Evan Dapo, a physician assistant. “Having what’s technically not even a surgical option is just amazing.”
Only about 1 in 80,000 babies is born with a condition such as Annalise’s. She was able to be treated with magnets because Hoover happened to know about the procedure from a medical article. “Not a lot of people know about it,” Hoover said. “There’s no sutures, no incisions.” Hoover contacted the inventor, Dr. Mario Zaritzky, a pediatric radiologist at the University of Chicago’s Comer Children’s Hospital; Zaritzky then traveled to Raleigh to advise WakeMed specialists.
Reached by phone Friday, Zaritzky said most children born with a partially missing esophagus have a foodpipe growing into their windpipe, or trachea. In those cases, surgery is required to disconnect the two wrongly fused pipes, and it makes sense to use surgery to repair the esophagus, too. In Annalise’s case, though, the foodpipe was not connected to anything else, just missing a section, so it made sense to try magnets without surgery. Even so, doctors had to wait for Annalise to gain at least 2 pounds before the magnet procedure could be performed.
Zaritzky’s device was developed and manufactured in Winston-Salem by Cook Medical. It was approved for humanitarian use in this country just two years ago.
While Annalise is the first to go through the magnet procedure without surgery, three others have been treated in the U.S. with a combination of magnets and surgery. And nine have been treated with the magnet procedure in Argentina, where Zaritzky originally came up with the concept. In all, the procedure has been used 13 times in the past 14 years, Zartitzky said. At WakeMed, doctors noted that Annalise’s magnet therapy stretched her foodpipe together within 36 hours. Once the magnets “mated,” her esophagus self-grafted within a week. “This is like a miracle,” said Dr. Duncan Phillips, WakeMed’s director of pediatric surgery. “I’ve been doing this for 19 years and I have never seen anything like this.”
Five year-old with special needs has achievements recognised
A FIVE-YEAR-OLD boy with special needs has won an award recognising his courage in overcoming his difficulties.
Casper Dowson, From ENGLAND, Etherley Dene, Bishop Auckland was awarded one of four schools’ awards at Shildon’s Children and Young People’s Action Network (SCYPAN) Young People’s Awards on Wednesday, November 25 at Shildon Civic Hall.
The determined and resilient boy, who attends the town’s Timothy Hackworth Primary School, suffers from XYY syndrome, a rare genetic condition affecting one in 3,500 boys. Males with the condition have an extra Y chromosome which tends to make them very tall. They may also suffer with learning and behavioural difficulties.
Casper was also born with oesophageal atresia, an abnormality in his gullet which makes eating difficult and for which he has had several operations. He also has problems with his balance and speech development.
Despite these challenges, Casper has proved himself a determined youngster, nowhere more so than at school. He was nominated for the school’s young achiever award by his headteacher, who, along with the school’s special needs co-ordinator, had no hesitation in rewarding Casper for his hard work and independence.
Casper’s mother, Val Dowson said: “He stood out for all the right reasons. He wasn’t chosen because of his conditions or his medical needs. He stood out because, against all the odds, he’s fought through and worked hard.”
Funded by Livin, Hays Travel, the Variety Show, Shildon Town Council and Darlington Chair Cover Hire, the awards evening recognised and rewarded the young people of the town for all their hard work and dedication over the past year.
Also receiving awards were: Lauren Atkinson (Arts Creative Award), the cast of Les Misérables from Sunnydale Campus Greenfield Community College (Arts Performing Award), Nicola Stevens (Sports Award) and Owena Saunders (Young Person’s Choice Award). Timothy Hackworth School Council – Ben Hopper, Jessica Costello, Brendan Haigh, Ethan Ingram, James Plews, Kristian Welch, John Taylor, Ashton Houlahan, Rachel Jones and Millie Sanderson – received the Community Champion Award.
As well as Casper’s, Schools Awards were presented to Sophie Story (Sunnydale Campus, Greenfield Community College), Anthony Scott (St. John’s C of E (Aided) Primary School) and Harrison Taylor from Thornhill Primary School.
The Chloe Clark Special Achievement and Recognition Award – awarded for determination through hardship – was presented to Mia Day, Matthew Harnett, Caity Connor and Keira O’Brien.
THIS SHOW’S Never give up hope x
40 surgeries in her 18 months
Angel Shane Robinson inspired by his family, including daughter who has had nearly 40 surgeries in her 18 months
Angels outfielder Shane Robinson poses with wife Jessica and their two daughters, Tinley, left, and Harper. The family does not get to see each other much because he is on the road and Harper has been in Boston for her care.
ANAHEIM – When Jessica Robinson looks at her 18-month-old daughter Harper, she sees some of the same traits that have helped her husband, Shane, forge his way to back to the major leagues. “She’s just like Shane,” Jessica said. “She operates with a chip on her shoulder. She fights pretty well for herself. You’d never know what she’s been through. Harper was born with esophageal atresia, a condition in which the esophagus doesn’t connect to the stomach. Harper has had nearly 40 surgeries, including 10 major procedures in which doctors have opened up her chest or abdomen. Every meal of her young life has come through a feeding tube that connects directly to her small intestines.
“She’s been through quite a bit,” Shane said. “But you would never know if you saw her. She’s super happy.” While Robinson, an Angels outfielder, has been clinging to a baseball career that has included four organizations in the past two years, his wife has been doing the hard part.
Jessica has been toting two kids – including 4-year-old daughter Tinley – around the country. Jessica and the girls spend much of their time in Boston, where a children’s hospital specializes in esophageal atresia. Otherwise, they go between their home in Atlanta and wherever Robinson is playing. Besides occasional visits from his family, Robinson relies on FaceTime to maintain contact. In that sense he is like many baseball dads who are away from their families. It’s common for players away from home to feel tugged in two directions, but it’s even more complicated in a situation such as Robinson’s.
“Baseball kind of helps me because I can be engaged and hang out with the guys and it takes my mind off it,” Robinson said. “The worst part is knowing my wife is dealing with most of it when I’m away. I try to be aware of that as much as possible. It’s tough. ”Robinson, 31, was drafted by the St. Louis Cardinals out of Florida State in 2006 and reached the majors in 2009. He bounced between the majors and minors for a few years. In 2013, he homered against the Dodgers in the NLCS and played in the World Series.
At 5-foot-9, Robinson is the prototypical undersized overachiever. Fans in St. Louis so appreciated him, despite his limited role, that they greeted him with a standing ovation when he returned last year as a member of the Minnesota Twins. The elements of Robinson’s makeup that the Cardinals and their fans enjoyed so much are exactly what Jessica would come to see in their daughter.
Before Harper was born, the Robinsons learned from prenatal testing that something was wrong. It turned out she had the rarest form of her condition. From the moment Harper was born, her life was a series of agonizing ups and downs.
“It’s kind of a roller coaster,” Shane said. “We’ve had big setbacks. It’s been back and forth her whole life.”
All the while, Robinson has been dealing with the life of a major league 25th man. The Cardinals released him around the time Harper was born. The Twins signed Robinson and he spent most of the 2015 season in the majors, but he had to leave the team on three occasions to join the family for one of Harper’s operations. “As a guy, you try to take as much as you can on your shoulders,” Robinson said. “It’s tough with them being in Boston and me being in Minnesota. I tried to stay focused on my job to provide and go out there and produce on the field.”
Jessica said there were times when her husband wanted to stop playing baseball entirely so he could be with them, but she talked him out of it.
“There’s been a couple conversations we’ve had about whether he should be in Boston or continue playing baseball,” Jessica said. “I’m confident with what I’m doing. It’s extremely hard, but when he goes back to baseball, his focus is not what he can do in his career, but it’s more how he can provide for his family.”
To get an idea of the Robinsons’ perspective, Jessica said Shane’s promotion to the Angels this week was a blessing because the insurance is much better for a major leaguer than a minor leaguer. Jessica also said all of Shane’s organizations have been helpful. “We’ve gotten a ton of support from the baseball community, the Boston wives, the Twins wives and the Cardinals wives,” Jessica said. “We’ve gotten so much support.” Former Red Sox pitcher Wade Miley let the Robinsons stay at his place during one of their extended stays in Boston. Meanwhile, over the winter Robinson was again looking for a job after the Twins released him. The Cleveland Indians signed him and he expected to have a shot to make the team. But the Indians then added veteran outfielders Marlon Byrd and Will Venable, squeezing out Robinson. Just as he was dealing with that, there was an emergency with Harper, requiring Shane to leave spring training for Boston. Her esophagus had attached to one of her lungs, requiring yet another procedure. The operation went well and the Robinsons are actually optimistic they are nearing the finish line with Harper, who may soon be able to begin learning to eat normally.
That good news roughly coincided with the Angels offering him a deal after he had exercised the out clause in his contract with the Indians. After four weeks in the minors with the Angels, Robinson got a shot to return to the majors because of Craig Gentry’s back injury. His family seized the opportunity to come see him in Milwaukee this week, the first time they’d been together since March.
The girls smothered Robinson when they saw him. “They love their dad so much,” Jessica said. “It was worth every hassle through the airport to get out and see him.” After two days in Milwaukee, the Robinsons headed back to Atlanta for a brief break before a return to Boston for more tests.
If all goes well, the family may be able to reunite more regularly and for longer periods, wherever Robinson is playing. Soon, they are hoping, the daily challenges will not involve surgeries or hospitals, but simply learning to do all the things that a normal little girl learns. Babies with her condition are normally behind their peers in growth and development. But Jessica looks at Harper and sees Shane.
An undersized overachiever.
“She’s a fighter,” Jessica said. “She’s catching up for her age. She’s not walking yet. She conquered crawling. She’s a little bit behind, but she’s pretty determined.”
My Baby Was Born With VACTERL Association:
One Mom’s Story
Coping with a scary diagnosis just moments after birth
Click on the underlined RED Writing
Help from the air
Phoebe’s Flight to Carins
We went on a Family holiday to visit the Top of Australia, Cape York. It’s a massive drive in the 4×4 with the camper in tow, we had planed it for over 6 months.
We drove through the day and camped at night finally we got to our destination where we spent 4 days exploring it was beautiful, relaxing and priceless.
On our way home we stopped at some waterholes and Phoebe started to get temperatures and a crackle sound on her back. I gave her panadol suppositories and it brought the temps down during the day but at night was when it was the worst, by the 3rd day her temps were really high a chesty cough and her breathing was very tugging in her throat and just below her ribs on her belly. She was struggling and very tired. The closest hospital was more than a 4 hour drive away and it was still dark when we left at 4.30am along corrugated dirt roads to get to the Weipa Hospital. When we arrived, we were taken straight in and I explained about Phoebe being born with TOF – OA unable to swallow and that the bad cough that she had was partly normal it was the wetness on top of the cough that I was concerned about. She was dehydrated and needed some oxygen, so to get the fluids into her by drip the Doctor decided it was best if Phoebe was sedated as when they were putting the nasal prongs across her nose she would just rip them off.
Phoebe had an x-ray of her chest and it showed that she had Pneumonia.
Phoebe started to deteriorate and was struggling to breathe, I thought that we could lose her, It was just a cold? I cried. That’s when the Doctors decided to send Phoebe by plane with the Royal Flying Doctors to the Cairns Base Hospital.
It all got very scary when the Doctors were talking about intubating her so she was safe on the plane, But this frightened me so much I had explained that I was concerned about them doing damage to her esophagus or her not waking up so they rechecked her gases this test measures the level of O2, Carbon Dioxide, pH and others in her blood and they came back and made the decision to let her board the plane the way she was. Brad and the Boys stayed behind at Weipa to get a good nights sleep before driving 10 hours to Cairns.
The flight from Weipa to Cairns was only 2 hours, I hadn’t been in a small plane before I was nervous but when I saw above the clouds I felt calm and I knew that Phoebe was going to be OK today we were only visiting Heaven.
On the plane Phoebe asked for a bottle of milk and the Doctor said it was fine, it was the first bottle she had in 4 days.
We arrived in Cairns and over 4 days she improved on oxygen antibiotics and ventolin.
We were discharged, then continued to travel home.
We as a Family would very much like to thank the Royal Flying Doctors of Australia for their dedication and total commitment in the job they do.
Sydney Children’s Hospital and TOF information sheet
New helicopter takes off with Theo and Sheffield medical team ENGLAND 16 May 2013
A baby boy who needed emergency surgery was the first to be flown in a new charity helicopter supported by a Sheffield medical team.One day old Theo Mikova was transferred on a 15 minute flight from Scarborough Hospital to Hull Royal Infirmary after his mum gave birth during an emergency caesarian.The Children’s Air Ambulance charity’s lone helicopter is the country’s first dedicated to youngsters and used the medical team from the Embrace Yorkshire & Humber Infant & Children’s Transport Service, www.thechildrensairambulance.org.uk/ to keep him stable.
After a difficult labour mum Denisa Mikova (19) had to be put to sleep to give birth to baby Theo, born at 4lb 14oz, five days late. Once Theo arrived doctors realised he needed an operation on his gullet (oesophagus) which did not join correctly to his stomach and could have made him very ill. Dad Lee Ratchford (26), of Scarborough, North Yorkshire, said: “My girlfriend came round and was still in a lot of pain and we got her into her own little room.
“That was when the doctor came and explained to us about what was wrong with him and that he needed surgery. As soon as the word surgery came in I started crying and so did Denisa. “But we were assured everything would be alright and that was when we found out he would be transferred to Hull. We thought we would be going by ambulance but then the helicopter came for him.”
He was transferred for emergency surgery via The Children’s Air Ambulance, while being looked after on board by The Children’s Hospital, Sheffield’s Embrace medical team. This was the first emergency airlift of its kind to happen with the Children’s Air Ambulance and Embrace teams. Meanwhile Denisa and Lee travelled an hour to Hull in an ambulance to join him when he came out of theatres. “It took 15 minutes and by road it was about an hour,” Lee added. “I do appreciate a lot about what that ambulance did for us. We were an hour and if that hadn’t been there Theo would have had to wait an hour in the ambulance with all the shaking around.”
Theo had a tracheo-oesophageal fistula operation and is now recovering well with no expected complications.
Dr Stephen Hancock, Lead Consultant for Embrace, which is part of Sheffield Children’s NHS Foundation Trust, was in charge of the infant’s care on board the flight.He said: “Embrace were delighted to work with The Children’s Air Ambulance on their first ever emergency transfer, providing the medical and nursing teams to help get this child to the right hospital for surgery fast.
“All the teams involved have been working really hard to get to this point and it is gratifying to see the helicopter in the air. “This service is so vital because quicker transfer times mean that our medical teams are available to look after more critically ill children in the north of England.” The Children’s Air Ambulance aims to slash the time it takes to get children to specialist hospital units. The helicopter features the latest paediatric and intensive care equipment and travels up to 200mph. Before the service, sick children often faced road journeys which could take hours depending on the distance involved.
Chief executive Andy Williamson said the charity would increase survival rates by reducing travel times and allowing specialists to accompany sick children during the journey.He said: “Around 5,800 critically ill children every year require transportation from and between paediatric intensive care units. “When a child is suffering from a serious illness, the specialist life-saving treatment they need can sometimes be hundreds of miles away.
“Journeys by land can take considerable time, as well as being uncomfortable and distressing for the child, and often medically challenging.”
Our lifesaving missions are funded by your generous donations. We do not receive any government funding. www.thechildrensairambulance.org.uk/